School of Computational & Integrative Sciences, JNU, New Delhi
Indira has vast experience of working in Industry and academia in the field of Biophysics, Computational Biology & Chemoinformatics leading to aid of drug designing in infectious diseases. She has worked in AstraZeneca for 13 years ( 1990-2013) in lead designing in projects associated with unmet diseases like Tuberculosis and Malaria. Since last ten years her experience has been enriched in academia as Director of Bioinformatics, University of Pune and Professor /Dean, School of Computational & Integrative Sciences , JNU Delhi.
She has been actively training human resources in the fields of Bio and Chemoinformatics and provided 7 Phd and 35 MSc/Mtech project trainees in the field of Computational Biology & Bioinformatics. She has a Master degree in Physics from Calcutta University and PhD from Indian Institute of Science , Bangalore with a long post doctoral experience in Andy McCammon’s lab where she worked as Fulbright scholar during 1983-86.She has been associated with the Royal Institute of Technology and Karolinska Institute, Stockholm, Sweden during 1987-93. She has been one of the pioneers in propagating education in Computational biology and Chemoinformatics in Indian Universities and is the member of task force in ICMR (medical informatics) & DeiTY ( Computational Biology group) which encourage medical professionals and computer science graduates to work in the interdisciplinary research area like Systems Biology & Synthetic Biology.
She has organized many workshops and conferences, and is presently Steering Committee member of International Translational Bioinformatics Conference (http://www.aporc.org/ISB/2014/).She has been a faculty member of Research Training on Intracellular Pathogen workshop under U.S.-India Joint Research Training Program (2011-2014: http://www.seattle-india-gid.org/) and has been a member of OpenTox project funded by European commission. 2008 -2011 (www.opentox.com). She has been a member of QSAR & Chemoinformatics Society since 2004. Her publications and present research interest etc. are available in details at her website: http://ccbb.jnu.ac.in/ig-web/in_home.html and http://www.jnu.ac.in/FacultyStaff/ShowProfile.asp?SendUserName=indira
|01.||A plausible mechanism for the antimalarial activity of artemisinin: A computational approach by Ashutosh Shandilya, Sajeev Chacko, B. Jayaram & Indira Ghosh. in Nature SCIENTIFIC REPORTS (2013) August29, 3 : 2513 DOI: 10.1038/srep02513|
|02.||Unusual domain architecture of aminoacyl tRNA synthetases and their paralogs from Leishmania major, Rentala Madhubala, V S Gowri, Indira Ghosh, Amit Sharma in BMC Genomics ( 2013).|
|03.||Concepts on the protein folding problem ,Jean-Numa Gillet and Indira Ghosh in Journal of Biomolecular Structure and Dynamics, online 2013, http://dx.doi.org/10.1080/07391102.2012.748546|
|04.||Hosseini Ashraf, Indira Ghosh, Pramod Khandekar, Mohammad Hiresh Ayoubian, Simple sequence repeats in specific gene groups of shigella genome, IOABJ; Vol. 4: Issue 1;17–24(2013).|
|05.||Methylerythritol phosphate pathway to isoprenoids: Kinetic modelingand in silico enzyme inhibitions in Plasmodium falciparum. By Vivek Kumar Singh, Indira Ghosh in FEBS LETTERS (2013) .|
|06.||Modeling and Experimental Analyses Reveals Signaling Plasticity in a Bi-Modular Assembly of CD40 Receptor Activated Kinases by Uddipan Sarma, Archana Sareen, Moitrayee Maiti, Vanita Kamat, Raki Sudan, Sushmita Pahari,Neetu Srivastava, Somenath Roy, Sitabhra Sinha, Indira Ghosh, Ajit G. Chande, Robin Mukhopadhyaya, Bhaskar Saha in PLoS ONE 7(7): July 2012 e39898 doi:10.1371/journal.pone.0039898|
|07.||Oscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops. Uddipan Sarma & Indira Ghosh in BMC Research Notes. Nov. 2012, 5:287|
|08.||Different designs of kinase-phosphatase interactions and phosphatase sequestration shapes the robustness and signal flow in the MAPK cascade , Uddipan Sarma & Indira Ghosh in BMC Systems Biology July 2012, 6:82|
|09.||Functional relevance of dynamic properties of dimeric NADP-dependent isocitrate dehydrogenases, Rithvik Vinekar, Chandra Verma, Indira Ghosh in BMC Bioinformatics (2012) Volume 13 Supplement 17, S 2.|
|10.||Fractal symmetry of protein interior: what have we learned? Anirban Banerji & Indira Ghosh in Cellular and Molecular Life Sciences , (2011) Aug;68(16):2711-3726.|