Applications of
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Duraiswami, C



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About Chaya Duraiswami (GlaxoSmithKline)
Chaya Duraiswami obtained her Ph.D. in medicinal chemistry from the University of Illinois at Chicago where she developed the 4D-QSAR method under the guidance of Professor Tony Hopfinger. She also validated the application of the 3-way PLS algorithm in the derivation of 3D-QSAR models under the guidance of Professor William Dunn III. She then joined Avon Skincare Laboratories in Suffern, NY, to start a computational chemistry group that focused its efforts on the discovery of new skincare molecules to address pigmentation and skin aging-related conditions. In 2000 she joined Pharmacopeia, in Princeton, NJ, as a computational chemist designing combinatorial libraries, and optimizing inhibitors for potency, selectivity and ADME properties for various alliance projects. Since 2002 she has been a member of the Computational Chemistry group at GlaxoSmithKline, in Collegeville, PA, where she has designed inhibitors for various pharmaceutical targets, and has co-developed a lead-hopping approach called SCOPE. Her interests include both ligand and structure-based approaches to drug design.

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